Veoza is a new, non‑hormonal treatment for menopausal hot flushes and night sweats that is now available on the NHS. Read below to see why it is different from HRT and the pros and cons.
The Science
Its active ingredient is fezolinetant, a medicine that works on a specific brain pathway involved in temperature control. During menopause, falling oestrogen disrupts the balance between oestrogen and a brain chemical called neurokinin B (NKB). This imbalance makes the brain’s temperature centre overreact, causing sudden heat, sweating and sleep disruption. Veoza blocks NKB, helping the temperature system settle down.
This makes Veoza different from HRT, which replaces falling hormones with oestrogen (and progesterone if needed). HRT can help with a wide range of symptoms — sleep, mood, joint pain, vaginal dryness, bone health — because it restores hormone levels. Veoza focuses specifically on hot flushes and night sweats and does not contain hormones.
Why Veoza instead of HRT?
Some women may prefer Veoza because it is non‑hormonal, or because they cannot take HRT for medical reasons. Others may find HRT more suitable because it supports multiple symptoms and has long‑established benefits. Both treatments have specific risks, benefits and monitoring requirements, and a clinician can help determine what is appropriate.
Veoza represents an important new option, especially for women seeking non‑hormonal support.
Comparison:
Only a clinician can help decide which is appropriate, because both have specific risks, benefits and monitoring requirements.
To read a BBC article on Veoza, click here.
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